Web Site of the Department

Head of the Department: Kutlu Ulgen

Professors: Sukru Ugur Akman, Ahmet Erhan Aksoylu, Mahir Arikol*, Bahattin
Baysal*, Fahir Borak*, Mehmet C. Camurdan, Salih Dincer*, Pemra Doruker,
Turkan Haliloglu, Amable Hortacsu*, Oner Hortacsu*, Betul Kirdar, Stephan G.
Oliver•, Zeynep Ilsen Onsan, David L. Trimm•, Kutlu Ulgen, Ramazan Yildirim

Associate Professors: -
Assistant Professors: Ahmet Kerim Avcı, Murat Dervisoglu, Elif Ozkirimli
Olmez, Abdullah Kerem Uguz

*Part-time

• Adjunct

The department endeavors to provide for the needs of the chemical industry and for research in Chemical Engineering. The aim is to train engineers who will be mainly concerned with the development and application of manufacturing processes in which chemical, biochemical, and/or physical changes of materials are involved and who will be able to design, construct, operate and maintain the equipment in which these operations and processes will take place.

The undergraduate program has four specialization-option sequences: Biomolecular Engineering, Catalyst Technologies and Reaction Engineering, Polymer/Biopolymer Science and Engineering and Process Engineering. Each student must select one option sequence from which at least three courses must be completed. Students doing double-major programs in science or engineering may take a specialization-option sequence from their second major. In addition, all students choose three complementary courses with a view toward complementing their engineering education according to their individual interests; these courses may also be selected so as to complete a second option sequence. The selection of specialization-option and
complementary courses must be made under the supervision of the departmental
advisors.

The course requirement for the Bachelor of Science Degree in Chemical Engineering is a minimum of 143 credit-hours of formal course work. In addition to the course-credit requirements, the equivalent of minimum 60 work-days of industrial training in areas approved by the department, in the two summers following the second and third years, is required.

UNDERGRADUATE PROGRAM

TOTAL: 143 credits

 SPECIALIZATION OPTIONS AND CREDITS  

(1) At least four courses should be taken from an option list to satisfy the option requirements.
(2) Special Topics courses, depending upon the subject they will cover in a given semester, may be included in one ore more Specialization Option course lists upon Departmental decision.

COURSE DESCRIPTIONS

CHE 110 Introduction to Chemical and Biosystems Engineering (4+2+0) 4
(Kimya ve Biyosistem Muhendisligine Giris)
Introduction and history of chemical and biochemical engineering. Chemical industries and industrial biotechnology applications in Turkey. Principles and applications of material balance calculations of continuous steady-state processes. Introduction to process flowsheet simulation, computational techniques and software applications. Introduction to chemical engineering design and economics.

CHE 201 Physicochemical Systems I (Fizikokimyasal Sistemler I) (3+1+0) 3
Description of physicochemical systems. Laws of thermodynamics. Changes of state. Solutions and phase equilibria. Chemical equilibrium. Physical chemistry of surfaces. The kinetic theory. Electrochemistry: conductance and ionic reactions; electrochemical cells.

CHE 202 Physicochemical Systems II (Fizikokimyasal Sistemler II) (3+1+0) 3
Concepts and methods of statistical thermodynamics. Distribution of molecular states. Schrodinger equation, partition functions, X-ray diffraction. Electric and magnetic properties of molecules. Structure and motion of fluids. Radial distribution functions. Intermolecular forces. Kinetics of gases, diffusion equation. Chemical kinetics, rate laws, temperature dependence of reaction rates, elementary and complex reactions. Eyring's theory. Laboratory experiments.

CHE 203 Physicochemical Systems Laboratory (0+0+2) 1
(Fizikokimyasal Sistemler Laboratuvarý)
Experimental techniques and analysis of data in physicochemical systems. Experiments related to the properties of pure gases, liquids and mixtures, phase diagrams, electrochemistry, rate of chemical reactions and catalysis

CHE 211 Mass and Energy Balances (Kutle ve Enerji Denklemleri) (4+2+0) 4
Calculation methods used in chemical and biochemical engineering based on principles of material and energy balances. Application of equations of state, heat capacity, enthalpy, chemical reactions, two-phase systems, enthalpy-concentration diagrams, heats of solution crystallization, vaporization, melting etc. Simultaneous material and energy balance calculations of chemical and biochemical engineering unit operations, unit processes and related applications.
Prerequisite : CHE 110

CHE 222 Introduction to Biosystems (Biyosistemlere Giris) (3+0+0) 3
Introduction to the molecular biology of the cell. Cellular metabolism, metabolic, regulatory and signalling networks. Bioinformatic tools and data banks. Systems biology approach to design problems in biotechnology .

CHE 232 Fluid Mechanics (Akiskanlar Mekanigi) (3+1+0) 3
Dimensional analysis with applications. Fluid statics and its applications. Integral and differential mass, energy and momentum balances. Laminar and turbulent flow of Newtonian fluids. Flow measurements.
Prerequisites: CHE 110, PHYS 121, Math 102.

CHE 302 Chemical Engineering Laboratory (1+1+4) 3
(Kimya Muhendisligi Laboratuvari)
Safety assessment. Principles of safety regulations. Survey of experimental methods. Series of experiments related to unit operations and unit processes.
Corequisites: CHE 334, CHE 342.

CHE 310 Introduction to Macromolecular Systems (3+0+0) 3
(Makromolekuler Sistemlere Giris)
Basic concepts of polymer science and engineering. Mechanisms and kinetics of polycondensation and free radical polymerization reactions. Molecular weight distributions. Addition copolymerization: random and alternating, block and graft copolymers. Definition of theta state and conditions. Osmometry, viscosimetry, gel permeation chromatography and dielectric and spectroscopic methods for the characterization of polymeric materials. Introduction to structure-property relationships.
Prerequisite: 3rd year standing.

CHE 321 Chemical Engineering Thermodynamics (4+1+0) 4
(Kimya Muhendisligi Termodinamigi)
The laws of thermodynamics, equations of state and formulation of thermodynamic properties of systems. Generalized state properties. Prediction of behavior of multiphase and multicomponent systems. Chemical reaction equilibria. Thermodynamic analysis of processes.
Prerequisite:CHE 201.

CHE 330 Separation Technologies (Ayirma Teknolojileri) (3+0+0) 3
Fundamentals of various separation processes and the tools necassary for selecting the most suitable separation sequence for a required task. Equilibrium-based processses such as distillation, evaporation, extraction, leaching, chromatography, absorption and stripping, absorption on ion-exchange resins, zeolites and activated coal as well as rate-governed processes such as membrane separation, reverse osmosis, ultrafiltration, dialysis, electrodialysis and gas separations by membrane permeation. Discussion of comparative energy requirements, economics, advantages and disadvantages of proposed separation tasks.
Prerequisite: CHE 211.

CHE 333 Heat Transfer (Isi Aktarimi) (3+1+0) 3
Heat transfer by conduction. Heat transfer by convection in single phase systems and in systems with phase change. Radiation heat transfer. Analytical, numerical and graphical techniques. Heat exchange equipment and networks.
Prerequisites: CHE 232, MATH 202.

CHE 334 Mass Transfer Operations (4+1+0) 4
(Kutle Aktarimi ve Temel Islemler)
General and special forms of the differential equations for mass transfer. Steady-state molecular diffusion. Convective mass transfer: single-phase and interphase transfer. Continuous and stagewise contacting of immiscible and partially miscible phases: gas absorption, desorption and liquid-liquid extraction. Distillation of binary mixtures.
Prerequisites: CHE 321, CHE 232.

CHE 342 Reaction Kinetics and Reactor Design (4+1+0) 4
( Reaksiyon Kinetigi ve Reaktor Tasarimi)
Kinetics of homogeneous reactions. Analysis of simple and complex rate equations; correlation of rate data. Kinetics of heterogenous reactions. Global rates. Isothermal and non-isothermal operation of homogeneous reactors: ideal batch, plug-flow and stirred-tank reactors. Other reactor types. Deviations from ideal performance.
Prerequisites: CHE 202, CHE 333.

CHE 353 Chemical and Biochemical Processes (3+0+0) 3
(Kimyasal ve Biyokimyasal Surecler)
A survey of various processes in chemical and biochemical industries in light of probable future developments. Critical analysis of chemical and biochemical processes in detail.
Prerequisite : CHE 110

CHE 383 Probability and Statistics in Chemical Engineering Applications
(Kimya Muhendisligi Uygulamalarinda Olasilik ve Istatistik) (3+1+0) 3
Fundamental concepts in probability; probability distributions, mathematical expectations; statistical methods including sampling distributions, point and interval estimation, hypothesis testing, linear regression, analysis of variance, as applied in chemical engineering problems. Factorial design of experiments.
Prerequisite: MATH 201.

CHE 386 Modeling and Optimization (Modelleme ve Optimizasyon) (3+0+0) 3
Mathematical modeling of steady-state and dynamic chemical engineering systems. Numerical solution of algebraic and differential equations, Basic optimization theory and algorithms with applications to chemical engineering problems. Process simulation techniques. Computer programming with Matlab.
Prerequisites: CHE 211, MATH 202

CHE 401 Chemical Engineering and Biotechnology Laboratory (1+0+4) 3
(Kimya Muhendisligi ve Biyoteknoloji Laboratuvari)
Continuation of ChE 302. Series of independent laboratory projects and presentations and proposals related to fluid flow, heat and mass transfer, and chemical reactions in chemical engineering as well as enzyme reactions and fermentation in biotechnology. Prerequisite : CHE 302

CHE 412 Structure, Function and Simulation of Biopolymers (3+0+0) 3
(Biyopolimerlerin Yapi, Fonksiyon ve Benzetimi)
Introduction to protein structure and conformations. DNA: mechanical properties and packing. Structural classes of proteins. Protein folding problem. Thermodynamics of protein denaturation. Hydrophobicity. Kinetics of biomolecular changes. Molecular motors and transcription machinery. Mechanism of protein-protein, protein-DNA, protein-inhibitor binding and interactions. Analysis of Protein Data Bank and Nucleic Acid Data Bank structures. Computational methods for simulating biomolecular systems. Methods in protein engineering and design.

CHE 413 Design and Simulation of Macromolecular Systems (3+0+0) 3
(Makromolekuler Sistemlerin Tasarimi ve Benzetimi)
Introduction to statistical mechanics of macromolecular systems. Models of different complexities for simulating polymers. On-lattice and off-lattice approaches for design and numerical analysis. Monte Carlo/Metropolis algorithms. Molecular forces dominating the stability and conformational kinetics of polymers. Molecular dynamics and Brownian dynamics simulations. Statistical analysis of simulation trajectories.

CHE 414 Physical Properties of Polymeric Systems (3+0+0) 3
(Polimer Sistemlerinin Fiziksel Ozellikleri)
First and second order transitions in polymeric materials: glass transition and phase transition phenomena. Flory-Huggins theory. Equation of State Approaches. Frictional properties of polymers in solution. Viscoelastic models for the description of the mechanical behavior of polymer in the bulk state. Rubber elasticity.
Prerequisite: CHE 310.

CHE 421 Genetic Engineering Applications in Biotechnology (3+0+0) 3
(Biyoteknolojide Genetik Muhendisligi Uygulamalari)
Introduction to molecular biotechnology, DNA replication, transcription, genetic code, translation, post-transcription and post-translational modifications, control of genetic expression, mutation and mutagenesis. Basic principles of genetic engineering and its applications in medicine, agriculture, and in the production of commercially important proteins.

CHE 422 Molecular Biotechnology (Molekuler Biyoteknoloji) (3+0+0) 3
High-throughput technologies and data analysis in omics. Genomics, proteomics and metabolomics. Post-genomic developments in life sciences and their applications in biotechnology. The use of bioinformatic tools and data banks in functional genomics. Rational design for biological processes and product development through metabolic and genetic engineering.
Prerequisite: CHE 421

CHE 425 Technology of Food Preservation (3+0+0) 3
(Gýda Koruma Teknolojisi)
Microbiological and biochemical considerations in food preservation. Discussion of various food preservation methods in detail. Food packaging and storage as related to the retention of organoleptic properties of fresh and processed foods.

CHE 426 Food Engineering (Temel Gýda Muhendisligi) (3+0+0) 3
Food raw material properties as related to process effectiveness, preliminary preparation operations (cleaning, sorting, grading), main conversion operations (size reduction, emulsification, mixing, filtration, extraction, crystallization, centrifugation), preservation methods (heat processing, dehydration, freezing, irradiation) applied and some relevant equipment used in food process industries.

CHE 427 Bioreaction Engineering (Biyoreaksiyon Muhendisligi) (3+0+0) 3
Kinetics of enzyme-catalyzed reactions. Modeling of microbial growth and product formation kinetics in cell cultures. Transport phenomena in bioreactors. Introduction to design and analysis of bioreactors, selection and scale-up. Examples of industrial bioprocesses and biotechnology products.
Prerequisite: CHE 342

CHE 430 Separation Processes (Ayirma Surecleri) (3+0+0) 3
Rate- and equilibrium-based separations. Generalized and specific rigorous multi-component steady-state and dynamic models of separation operations. Comparison of rigorous and short-cut methods. Computational methods with emphasis on multi-stage/multi-component separation: system models. Heuristic and MINLP approaches to separation systems. Heat integration in separation systems.
Prerequisite: CHE 334.

CHE 433 Design of Chemical Processing Units (3+2+0) 3
(Kimyasa Islem Birimlerinin Tasarimi)
Basic engineering concepts and accepted procedures as applied to the design of main process units and auxiliary equipment. Operating principles of various processing equipment to critically evaluate, specify and design the most appropriate unit(s) among available alternatives for specific tasks.
Prerequisites: CHE 334, CHE 342.

CHE 440 Heterogeneous Catalysis (Heterojen Kataliz) (3+0+0) 3
Physical and chemical properties of heterogenous catalytic systems. Metal catalysis, metal-support interactions. Measurement of catalytic properties. Criteria and methodologies involved in the selection, development and preparation of solid cataysts. Kinetics of fluid-solid catalytic reactions; model discrimination and parameter estimation. Interphase and intraparticle transport processes in heterogenous systems using porous ad non-porous solid catalysts. Global rates. Practical examples tracing the steps in process synthesis from catalyst selection up to its use in the industrial unit.
Prerequisite: CHE 342.

CHE 441 Hydrogen Technologies (Hidrojen Teknolojileri) (3+0+0) 3
Hydrogen as a clean energy source. Catalytic hydrogen production from hydrocarbons: steam reforming, autothermal reforming and partial oxidation. Hydrogen production using electrolysis, solar energy and boron technologies. Hydrogen purification by water-gas shift, preferential oxidation and other technologies. Storage and utilization of hydrogen.
Prerequisite: CHE 342

CHE 442 Design of Solid Catalysts (Kati Katalizorlerin Tasarimi) (3+0+0) 3
Scientific basis of solid catalyst design. Design of the primary active constituent. Secondary component design by mechanistic studies. Choice of support materials. Selection of catalyst preparation techniques. Experimental methods of catalyst testing. Production of industrial catalysts: unit operations and manufacturing procedures. Specific examples of catalyst design.
Prerequisite: CHE 342

CHE 444 Fuel Cells and Catalysis (Yakit Hucreleri ve Kataliz) (3+0+0) 3
Basic principles associated with fuel cells. Fuel cell types. Fuel cell catalysts and catalytic processes. Fuel cell thermodynamics and kinetics. Fuel cell operation, characterization and design. Combined fuel processor-fuel cell systems.
Prerequisite: CHE 342

CHE 450 Energy Technologies (Enerji Teknolojileri) (3+0+0) 3
Overview and classification of energy sources and energy technologies. Coal, petroleum, and natural-gas industries. Renewable energy sources and technologies. Biodiesel production. Hydrogen industries and fuel cells. Energy production, cogeneration, energy integration, energy recovery, and exergy analysis. Heat pumps, steam generators, turbines, and expanders. Energy and environment.
Prerequisite: 4th-year standing

CHE 460 Total Quality Engineering in Chemical Industries (3+0+0) 3
(Kimya Sanayinde Toplam Kalite Muhendisligi)
Introduction to quality management: fundamentals, historical background, technical and behavioral dimensions. Quality in design and development: conceptual and technical design, planning and integrating product and process design using Quality Function Deployment, robust product, parameter and process design using Taguchi methods. Quality assurance standards for design and production: ISO 9000 quality assurance systems, ISO 14000 enviromental management systems, as applied in chemical engineering practice.
Prerequisite: 4th year standing.

CHE 462 Plant Design and Economics (3+2+0) 3
(Kimya Tesislerinin Tasarimi ve Ekonomisi)
Study of fundamental concepts in chemical plant design, organization of chemicals manufacturing plants and the economic considerations associated with the investment, feasibility and operation of such plants. Independent and group projects covering the above topics related to the existing Turkish conditions.
Prerequisites: CHE 334, CHE 342.

CHE 463 Bioprocess Design (Biyosurec Tasarimi) (3+0+0) 3
Separation and purification technologies for biochemicals. Integration of individual unit operations, analysis and evaluation of the production of therapeutics/pharmaceuticals using process simulation, scheduling and risk analysis tools. Mathematical modeling and scale-up of selected operations. Throughput analysis, debottlenecking and economic evaluation of several bioprocesses.

CHE 465 Operational and Environmental Safety of Chemical Plants (Kimyasal Madde Fabrikalarinda Isletme ve Cevre Emniyeti) (3+0+0) 3
Safety problems posed by chemical plants to human life and the environment. Various risk types that may be encountered in chemical plants due to their design, construction and operation. Methods of identification, measurement and mitigation of risks. The economics of risk abatement and mitigation measures
Prerequisite : 4 th- year standing

CHE 475 Process Dynamics and Control (Surec Dinamigi ve Denetimi) (3+1+0) 3
Dynamic modeling of linear and nonlinear chemical processes. Linearization. Laplace transforms. Stability of systems. Conventional feedback controllers. Dynamic behavior of feedback controlled systems. Controller design using frequency response techniques. Computer simulation of controlled and uncontrolled systems. Design of controls using simulation programs.
Prerequisite: CHE 386.

CHE 476 Computer Aided Process Design and Synthesis (3+0+0) 3
(Bilgisayar Destekli Surec Tasarimi ve Sentezi)
Process flowsheet simulators, simulation for process design and synthesis. Handling of recycle streams. Process superstructures. Optimization approaches in flowsheet synthesis. Heat and power recovery and integration. Heat-integrated distillation processes. Synthesis of heat-exchange, mass-exchange, reactor and wastewater-treatment networks and separation sequences. Process flexibility and operability. Design and scheduling of batch processes. Process and production planning, dynamic process flowsheet simulation.

CHE 477 Process Optimization (Surec Optimizasyonu) (3+0+0) 3
Fundamentals of analytical optimization. Survey of one dimensional line-search methods, and multi-dimensional unconstrained and constrained numerical optimization algorithms. Applications of linear programming, nonlinear programming, mixed integer linear/ nonlinear programming, and parameter estimation in chemical engineering. Feasible-path and infeasible-path techniques for chemical process flowsheet optimization.
Prerequisite: CHE 386.

CHE 478 Cost and Risk Engineering (3+0+0) 3
(Maliyet ve Risk Muhendisligi)
Introduction to cost engineering with cost comparison and equivalence. Depreciation and tax. Profitability measures. Cost scheduling, control and accounting. Project/equipment replacement and displacement analyses, and cost optimization. Introduction to risk engineering with basic probability and statistics; uncertainty, Monte Carlo simulation, alternative risk measures, value-at-risk (VaR). Risk-reward balancing, risk diversification, project/equipment portfolio selection, and risk optimization. Design and operation under uncertainty and risk.

CHE 479 Process Identification and Monitoring
(Surec Tanimlama ve Gozlemleme) (3+0+0) 3
Introduction to process identification. Data-driven approach to static and dynamic model development via topics such as basic statistics and regression, time-series, linear and nonlinear autoregressive models such as (N)ARX and (N)ARMAX; nonlinear identification via artificial neural networks. Data smoothing and filtering, input selection, validation, forecasting. Introduction to process monitoring via control charts and principal-component analysis (PCA); correlation analysis. Introduction to data reconciliation and fault detection.

CHE 492 Project (Bitirme Projesi) (0+0+8) 4
Listed under Engineering Core Courses.

CHE 480-499 Special Topics in Chemical Engineering (3+0+0) 3
(Kimya Muhendisliginde Ozel Konular)
Special topics of current interest in chemical engineering and chemical technology.

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Contact Information Bogazici University 34342 Bebek, Istanbul Tel: 0212 359 54 00